SCHEMBL4357519

SCHEMBL4357519

COC(=O)c1ccccc1S(=O)(=O)OC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA5A P35218 1/20 0.54
CA9 Q16790 1/20 0.54
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 8/20 0.47
HSD17B10 Q99714 3/20 0.47
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GAA P10253 2/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
TSHR P16473 3/20 0.44
POLB P06746 1/20 0.43
ALOX12 P18054 1/20 0.43
RECQL P46063 1/20 0.43
RIPK1 Q13546 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409064 0.80 CA1 (0.47) CA1CA2KDM4EALDH1A1NPSR1
SCHEMBL1015878 0.78 CA1 (0.58) CA1CA2CA5ACA9KDM4E
SCHEMBL3170827 0.77 CA1 (0.69) CA1CA2CA5ACA9KDM4E
SCHEMBL6404705 0.76 ALDH1A1 (0.54) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL868426 0.76 ALDH1A1 (0.47) CA1CA2KDM4EALDH1A1GAA
SCHEMBL4599910 0.75 CA1 (0.58) CA1CA2CA5ACA9KDM4E
SCHEMBL8338879 0.74 ALDH1A1 (0.48) CA1CA2ALDH1A1GAANPC1
SCHEMBL4360015 0.74 CA1 (0.65) CA1CA2CA5ACA9KDM4E
SCHEMBL11661242 0.73 CA1 (0.73) CA1CA2CA5ACA9KDM4E
SCHEMBL11525036 0.73 GAA (0.46) CA1CA2CA5ACA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US claimed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US claimed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US claimed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA CA1 173/4885CA2 4/4885CA5A 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.