SCHEMBL435760

SCHEMBL435760

On1ccccc1=S.On1ccccc1=S.[NaH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.95
HSP90AA1 P07900 1/20 0.95
MMP3 P08254 1/20 0.95
CHRM1 P11229 1/20 0.95
TBXA2R P21731 1/20 0.95
PTGS1 P23219 1/20 0.95
LOX P28300 1/20 0.95
ADRA1A P35348 1/20 0.95
RAB9A P51151 1/20 0.95
GFER P55789 1/20 0.95
LOXL3 P58215 1/20 0.95
LOXL4 Q96JB6 1/20 0.95
LOXL2 Q9Y4K0 1/20 0.95
ALOX15 P16050 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CA12 O43570 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144753 1.00
SCHEMBL19900041 0.97 ESR1 (0.90) ESR1HSP90AA1MMP3CHRM1TBXA2R
SCHEMBL8333927 0.97 ESR1 (0.90) ESR1HSP90AA1MMP3CHRM1TBXA2R
SCHEMBL7054726 0.97 ESR1 (0.90) ESR1HSP90AA1MMP3CHRM1TBXA2R
SCHEMBL2427022 0.97 ESR1 (1.00) ESR1HSP90AA1MMP3CHRM1TBXA2R
SCHEMBL24755 0.97
Iodide SCHEMBL1411907 0.95 ESR1 (0.86) ESR1HSP90AA1MMP3CHRM1TBXA2R
SCHEMBL7650956 0.95
SCHEMBL1250766 0.95
Hydrochloric Acid SCHEMBL11149339 0.95 ESR1 (0.95) ESR1HSP90AA1MMP3CHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012012049-A2 ANTIMICROBIAL COMPLEXES LIU HUIWEN (US) 2012-01-26 WO disclosed