Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27610753 | 0.97 | MEN1 (0.41) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Acetic Acid SCHEMBL2523008 | 0.90 | FFAR3 (0.44) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Oxalic Acid SCHEMBL28604501 | 0.90 | MEN1 (0.41) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Pivalate SCHEMBL4916743 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| SCHEMBL2229652 | 0.83 | ALDH1A1 (0.37) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| SCHEMBL4924134 | 0.83 | MEN1 (0.41) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Maleic Acid SCHEMBL9798818 | 0.83 | TSHR (0.47) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| SCHEMBL5182685 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Maleic Acid SCHEMBL7128181 | 0.83 | TSHR (0.47) | MEN1KMT2ACYP1A2ALDH1A1THRB | |
| Fumaric Acid SCHEMBL2451025 | 0.83 | TSHR (0.47) | MEN1KMT2ACYP1A2ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119219550-A | Reduction method of carboxylic ester compound | 云南大学 | 2024-12-31 | — | — | CN | claimed |
| CN-113501779-B | Method for selectively removing benzyl, allyl and propargyl protecting groups by visible light or near visible light | 云南大学 | 2023-06-23 | — | — | CN | claimed |
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | claimed |
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |
| CN-113501779-B | Method for selectively removing benzyl, allyl and propargyl protecting groups by visible light or near visible light | 云南大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-107615556-B | Electrolyte and metal hydride battery | 巴斯夫公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113501779-A | Method for selectively removing benzyl, allyl and propargyl protecting groups initiated by visible light or near visible light | 云南大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | disclosed |
| EP-2033257-A4 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RES INST (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-2033257-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | Georgia Tech Research Corporation (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008054858-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20070259236-A1 | Anionic fuel cells, hybrid fuel cells, and methods of fabrication thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2007-11-08 | — | — | US | disclosed |
| EP-0930540-B1 | PHOTOSENSITIVE COMPOSITION AND USE THEREOF | SANYO CHEMICAL IND LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6727034-B1 | HIGH SENSITIVITY AND HIGH RESOLUTION; BLACK MATRIX AND PHOSPHOR SCREEN FOR A COLOR PICTURE TUBE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-27 | — | — | US | disclosed |
| EP-0930540-A1 | PHOTOSENSITIVE COMPOSITION AND USE THEREOF | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5538832-A | Developing solution for producing printed circuit boards and a process for producing printed circuit boards wherein the developing solution comprises a quaternary ammonium hydroxide and a quaternary ammonium carbonate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-07-23 | — | — | US | disclosed |