SCHEMBL4357758

SCHEMBL4357758

CC=CCCC=CCCC=CC=CC=CCCC=CCCC=CC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
CNR2 P34972 9/20 0.35
CNR1 P21554 7/20 0.35
TRPA1 O75762 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438876 0.90 CNR2 (0.42) PPARAPPARGPPARDCNR2CNR1
SCHEMBL8438874 0.90 CNR2 (0.42) PPARAPPARGPPARDCNR2CNR1
SCHEMBL4623652 0.86 TSHR (0.37) PPARAPPARGPPARDTSHR
SCHEMBL17748854 0.86 TSHR (0.37) PPARAPPARGPPARDTSHR
SCHEMBL1293140 0.86 TSHR (0.37) PPARAPPARGPPARDTSHR
SCHEMBL4623657 0.86 TSHR (0.37) PPARAPPARGPPARDTSHR
SCHEMBL1293139 0.86 TSHR (0.37) PPARAPPARGPPARDTSHR
SCHEMBL15974406 0.83 PPARG (0.36) PPARAPPARGPPARDCNR2CNR1
SCHEMBL15974405 0.83 PPARG (0.36) PPARAPPARGPPARDCNR2CNR1
SCHEMBL28777935 0.83 SOAT1 (0.47) PPARAPPARGPPARDCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090285919-A1 Rice Bran Extracts for Inflammation and Methods of Use Thereof HALPERN, BARUCH 2009-11-19 US disclosed