Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.42 |
| ▸ | CNR1 | P21554 | 7/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438874 | 1.00 | CNR2 (0.42) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL26624981 | 0.97 | CNR2 (0.41) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL21996121 | 0.94 | CNR2 (0.45) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL4357758 | 0.90 | PPARA (0.41) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL4357755 | 0.90 | PPARA (0.41) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL981668 | 0.88 | SOAT1 (0.44) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL981669 | 0.88 | SOAT1 (0.44) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL28777935 | 0.86 | SOAT1 (0.47) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL28777874 | 0.85 | SOAT1 (0.50) | CNR2CNR1TRPA1TRPV1PPARG | |
| SCHEMBL15305056 | 0.80 | CNR2 (0.39) | CNR2CNR1TRPA1TRPV1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990163-A | HYDROXY, EPOXY AND/OR CARBOXY DERIVATIVES OF METHOPRENE; ANTITUMOR,-CARCINOGENIC AND -PROLIFERATIVE AGENTS; SKIN DISORDERS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-11-23 | — | — | US | claimed |
| US-5990163-A | HYDROXY, EPOXY AND/OR CARBOXY DERIVATIVES OF METHOPRENE; ANTITUMOR,-CARCINOGENIC AND -PROLIFERATIVE AGENTS; SKIN DISORDERS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-11-23 | — | — | US | disclosed |