Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LONP1 | P36776 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863246 | 0.83 | CYP19A1 (0.38) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL11125408 | 0.79 | CYP19A1 (0.36) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL26833406 | 0.79 | CYP19A1 (0.43) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL781412 | 0.79 | CYP19A1 (0.43) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL781413 | 0.79 | CYP19A1 (0.43) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL179284 | 0.77 | CYP19A1 (0.42) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL31256061 | 0.77 | CYP19A1 (0.42) | CYP19A1KDM4ESMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL20774860 | 0.73 | CYP19A1 (0.40) | CYP19A1KDM4ESMN1; SMN2HSP90AA1LMNA | |
| SCHEMBL20128883 | 0.73 | CYP19A1 (0.40) | CYP19A1KDM4ESMN1; SMN2HSP90AA1NAPRT | |
| SCHEMBL8289716 | 0.73 | CYP19A1 (0.40) | CYP19A1KDM4ESMN1; SMN2HSP90AA1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497163-A | Synthesis method of dimethyl isobutyl pyrazine | PUCHENG YONGFANG FRAGRANCE TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | claimed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| CN-103497163-A | Synthesis method of dimethyl isobutyl pyrazine | PUCHENG YONGFANG FRAGRANCE TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | disclosed |
| US-20090032592-A1 | SPHERICAL ENCODED BEADS | NOVO NORDISK A/S (DK) | 2009-02-05 | — | — | US | disclosed |
| US-6579553-B1 | Reaction product cysteine, hydrogen sulfide, ammonium sulfide and extracellular liquid fusarium extracts used as food flavors | ZENECA LIMITED (GB) | 2003-06-17 | — | — | US | disclosed |