SCHEMBL435790

SCHEMBL435790

CC=C(C)OC(CC)c1ccc(N(CC)CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.46
CNR2 P34972 9/20 0.40
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PSMD14 O00487 1/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
GFER P55789 1/20 0.38
MAPT P10636 4/20 0.37
GRK6 P43250 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 2/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436221 0.89 MEN1 (0.40) ALDH1A1TSHRCNR2KDM4EMAPK1
SCHEMBL438129 0.86 GAA (0.41) ALDH1A1TSHRGAAL3MBTL1MAPT
SCHEMBL434881 0.83 ALDH1A1 (0.47) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL436344 0.74 CNR2 (0.39) ALDH1A1TSHRCNR2KDM4EMAPK1
SCHEMBL438069 0.69 ALDH1A1 (0.43) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL11197835 0.69 ALDH1A1 (0.58) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL8183747 0.68 ALDH1A1 (0.52) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL4116469 0.68 ALDH1A1 (0.56) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL131813 0.67 ALDH1A1 (0.56) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3
SCHEMBL10818964 0.66 ALDH1A1 (0.50) ALDH1A1TSHRCNR2ALDH3A1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US disclosed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed