Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.35 |
| ▸ | PGR | P06401 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358218 | 1.00 | NR3C1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL4358215 | 1.00 | NR3C1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL3533377 | 0.86 | NR3C1 (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3533375 | 0.86 | NR3C1 (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3533373 | 0.86 | NR3C1 (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3536662 | 0.84 | AXL (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3536665 | 0.84 | AXL (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3536664 | 0.84 | AXL (0.36) | NR3C1NR3C2PGR | |
| SCHEMBL3550311 | 0.83 | NR3C1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL3550307 | 0.83 | NR3C1 (0.35) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072509-A1 | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-24 | — | — | EP | disclosed |