SCHEMBL4358262

SCHEMBL4358262

CCCCc1ccc(-c2cc(Nc3ccccc3C)ccc2-c2ccc(-c3ccc(Nc4ccccc4C)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RARB P10826 3/20 0.39
HSD11B1 P28845 2/20 0.39
ATM Q13315 2/20 0.39
POLB P06746 1/20 0.39
PSMB5 P28074 1/20 0.38
MAPT P10636 3/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919586 0.95 MEN1 (0.39) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL1031878 0.85 KMT2A (0.49) MEN1KMT2AHSD11B1ATMPOLB
SCHEMBL919587 0.85 MEN1 (0.39) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL29977076 0.84 TRPV1 (0.46) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL9898781 0.84 TRPV1 (0.46) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL5617645 0.83 APP (0.42) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL3990792 0.82 TRPV1 (0.46) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL2207287 0.81 NPSR1 (0.45) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL3782358 0.81 RARB (0.39) MEN1KMT2ARARBHSD11B1ATM
SCHEMBL1726974 0.81 TRPV1 (0.43) MEN1KMT2ARARBHSD11B1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481237-B2 Photoconductor overcoat layer XEROX CORPORATION (US) 2013-07-09 US claimed
US-7618758-B2 Silanol containing perylene photoconductors XEROX CORPORATION (US) 2009-11-17 US claimed
US-7419750-B2 Imaging member having antistatic anticurl back coating XEROX CORPORATION (US) 2008-09-02 US disclosed