Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207287 | 0.90 | NPSR1 (0.45) | SMN1; SMN2HPGDMAPTLMNAMAPK1 | |
| SCHEMBL9898781 | 0.87 | TRPV1 (0.46) | APPSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL29977076 | 0.87 | TRPV1 (0.46) | APPSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL4823761 | 0.85 | HPGD (0.39) | SMN1; SMN2HPGDMAPTLMNAMAPK1 | |
| SCHEMBL5012296 | 0.85 | UCHL3 (0.44) | SMN1; SMN2HPGDMAPTLMNAMAPK1 | |
| SCHEMBL3990792 | 0.84 | TRPV1 (0.46) | APPSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL1726974 | 0.84 | TRPV1 (0.43) | APPSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL402791 | 0.84 | RARB (0.50) | SMN1; SMN2HPGDMAPTLMNAMAPK1 | |
| SCHEMBL1033861 | 0.83 | HPGD (0.53) | SMN1; SMN2HPGDMAPTLMNAMAPK1 | |
| SCHEMBL4358262 | 0.83 | MEN1 (0.41) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297457-B2 | Photosensitive member having an elastomeric transport layer with a protective overcoat layer | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-20060105252-A1 | Photosensitive member having an elastomeric transport layer with a thin overcoat layer | XEROX CORPORATION | 2006-05-18 | — | — | US | disclosed |
| US-20060099525-A1 | Imaging member | XEROX CORPORATION | 2006-05-11 | — | — | US | disclosed |
| US-20040126684-A1 | Imaging members | XEROX CORPORATION | 2004-07-01 | — | — | US | disclosed |