Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841077 | 0.82 | TSHR (0.43) | POLBNSD2NOS3NOS2ALDH1A1 | |
| SCHEMBL2679223 | 0.78 | POLB (0.32) | POLB | |
| SCHEMBL2680146 | 0.78 | DAO (0.33) | — | |
| SCHEMBL329259 | 0.78 | TDP2 (0.36) | TDP2NSD2HSP90AA1PAX8CYP3A4 | |
| SCHEMBL3356233 | 0.73 | CD44 (0.50) | POLBNOS3NOS2CYP3A4ALDH1A1 | |
| SCHEMBL21749799 | 0.73 | CD44 (0.34) | POLBCYP3A4ALDH1A1TDP1CD44 | |
| SCHEMBL9712590 | 0.73 | AR (0.36) | TDP2NSD2HSP90AA1PAX8CYP3A4 | |
| SCHEMBL9712649 | 0.73 | NCEH1 (0.38) | TDP2NSD2HSP90AA1PAX8CYP3A4 | |
| SCHEMBL394750 | 0.72 | POLB (0.68) | POLBTDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL28680385 | 0.71 | POLB (0.38) | POLBTDP2NSD2HSP90AA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373663-A2 | Castanospermine esters in the inhibition of tumor metastasis | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | claimed |
| US-4680144-A | HAIR CONDITIONERS | MALLINCKRODT, INC. (US) | 1987-07-14 | — | — | US | claimed |
| US-7635571-B2 | photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20040175696-A1 | Amplified luminescent homogeneous immunoassay | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-0373663-A2 | Castanospermine esters in the inhibition of tumor metastasis | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0110955-A1 | BRAIN-SPECIFIC DRUG DELIVERY. | UNIV FLORIDA (US) | 1984-06-20 | — | — | EP | disclosed |
| WO-1983003968-A1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIVERSITY OF FLORIDA (US) | 1983-11-24 | — | — | WO | disclosed |
| EP-0036426-A4 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. | INTERX RESEARCH CORP (US) | 1983-03-29 | — | — | EP | disclosed |
| EP-0036426-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. | INTERX RESEARCH CORP (US) | 1981-09-30 | — | — | EP | disclosed |
| WO-1981000849-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES | INTERX RESEARCH CORP (US) | 1981-04-02 | — | — | WO | disclosed |