SCHEMBL4358468

SCHEMBL4358468

C1=CC([Zr+2]2(C3C=CC4=C3CCCC4)CC2)C2=C1CCCC2.Cc1cc(C)c([O-])c(C)c1.Cc1cc(C)c([O-])c(C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4356700 0.88 SIRT1 (0.30)
SCHEMBL6358801 0.85
Hydrochloric Acid SCHEMBL8421241 0.81
Fluoride Ion SCHEMBL3469779 0.81
Hydrochloric Acid SCHEMBL10603904 0.81
Hydrochloric Acid SCHEMBL650348 0.81
Hydrochloric Acid SCHEMBL81441 0.81
Bromide SCHEMBL4364916 0.81
SCHEMBL7710009 0.81
SCHEMBL4364834 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619106-B2 Preparation of partially hydrogenated rac-ansa-metallocene complexes BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-20080200708-A1 Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes BASELL POLYOLEFINE GMBH (DE) 2008-08-21 US claimed
EP-1554295-B1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2008-07-02 EP claimed
EP-1554295-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES Basell Polyolefine GmbH (DE) 2005-07-20 EP claimed
WO-2004037838-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-05-06 WO claimed
US-7619106-B2 Preparation of partially hydrogenated rac-ansa-metallocene complexes BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US disclosed
US-20080200708-A1 Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes BASELL POLYOLEFINE GMBH (DE) 2008-08-21 US disclosed
EP-1554295-B1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2008-07-02 EP disclosed
EP-1554295-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES Basell Polyolefine GmbH (DE) 2005-07-20 EP disclosed
WO-2004037838-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-05-06 WO disclosed