SCHEMBL4358922

SCHEMBL4358922

O=C(O)c1cc(S(=O)(=O)c2ccc(F)c(C(=O)O)c2)ccc1F

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.59
LMNA P02545 2/20 0.54
APEX1 P27695 3/20 0.49
POLB P06746 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
VCAM1 P19320 1/20 0.47
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
SLC16A1 P53985 1/20 0.42
TSHR P16473 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ASPH Q12797 1/20 0.40
KDM8 Q8N371 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681795 0.93 CYP3A4 (0.57) CYP3A4LMNAAPEX1POLBCTDSP1
SCHEMBL29046703 0.93 CYP3A4 (0.57) CYP3A4LMNAAPEX1POLBCTDSP1
SCHEMBL29271857 0.86 HSD17B10 (0.62) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL283890 0.85 CYP3A4 (0.56) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL30035568 0.85 CYP3A4 (0.56) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL619999 0.85 LMNA (0.64) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL30525050 0.85 LMNA (0.64) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL572815 0.85 CYP3A4 (0.56) CYP3A4LMNAKDM4EALDH1A1HSD17B10
SCHEMBL1937987 0.82 LMNA (0.63) CYP3A4LMNAL3MBTL1KDM4EALDH1A1
SCHEMBL1397921 0.81 APEX1 (0.67) LMNAAPEX1POLBCTDSP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
EP-1788649-B1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
EP-1788649-A1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE Mitsui Chemicals, Inc. (JP) 2007-05-23 EP disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed