SCHEMBL4359614

SCHEMBL4359614

O=C(O)C=CNC=Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.63
HDAC3 O15379 3/20 0.63
HDAC4 P56524 3/20 0.63
HDAC2 Q92769 3/20 0.63
HDAC8 Q9BY41 3/20 0.63
HDAC6 Q9UBN7 3/20 0.63
HDAC7 Q8WUI4 2/20 0.63
HDAC10 Q969S8 2/20 0.63
HDAC11 Q96DB2 2/20 0.63
HDAC9 Q9UKV0 2/20 0.63
HDAC5 Q9UQL6 2/20 0.63
HCAR2 Q8TDS4 2/20 0.63
TNKS O95271 1/20 0.63
TNKS2 Q9H2K2 1/20 0.63
MAPT P10636 4/20 0.52
PLIN1 O60240 2/20 0.52
LMNA P02545 2/20 0.52
RECQL P46063 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL264894 0.82 MAOB (0.55) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL264895 0.82 MAOB (0.55) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL50466 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL653828 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL1332 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL1706935 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
(Z)-1,2-Diphenylethene SCHEMBL11804978 0.78 HDAC1 (0.81) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL3406486 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
Cinnamic Acid SCHEMBL653827 0.78 HCAR2 (1.00) HDAC1HDAC3HDAC4HDAC2HDAC8
(Z)-1,2-Diphenylethene SCHEMBL11804971 0.78 HDAC1 (0.81) HDAC1HDAC3HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872772-B1 Toner, developer, and process for producing the same SHARP KK (JP) 2002-10-23 EP claimed
EP-0872772-A1 Toner, developer, and process for producing the same Sharp Kabushiki Kaisha (JP) 1998-10-21 EP claimed
US-8470507-B2 Hybrid developing carrier, hybrid developing device and image-forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-06-25 US disclosed
US-20090154963-A1 HYBRID DEVELOPING CARRIER, HYBRID DEVELOPING DEVICE AND IMAGE-FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-06-18 US disclosed