SCHEMBL435981

SCHEMBL435981

C=[C]C(C=CC#N)C=C(C)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174505 0.71
SCHEMBL1789531 0.69
SCHEMBL6754232 0.68 HCAR2 (0.33)
Methacrylic Acid SCHEMBL5276743 0.64
SCHEMBL1543776 0.63 PTGS1 (0.30)
SCHEMBL793261 0.63 PTGS1 (0.48)
Acrylonitrile SCHEMBL28198565 0.63 ALDH1A1 (0.32)
SCHEMBL9065495 0.63
SCHEMBL82522 0.61
SCHEMBL82523 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020127834-A1 COMPOSITION OF THE GEL/GEL TYPE COMPRISING BORON NITRIDE PARTICLES AND AT LEAST ONE ENCAPSULATED PIGMENT L'OREAL (FR) 2020-06-25 WO claimed
CN-111067807-A Cosmetic composition for making up and caring for keratin materials 欧莱雅 2020-04-28 CN claimed
US-20180280258-A1 COMPOSITION COMPRISING A SOFT-FOCUS FILLER AND A COMPOSITE PIGMENT BASED ON NON-SPHERICAL ALUMINA AND ON A METAL OXIDE L'OREAL (FR) 2018-10-04 US claimed
EP-3362034-A1 COMPOSITION COMPRISING A SOFT-FOCUS FILLER AND A COMPOSITE PIGMENT BASED ON NON-SPHERICAL ALUMINA AND ON A METAL OXIDE L'OREAL (FR) 2018-08-22 EP claimed
EP-2826460-B1 Emulsion containing a dispersion of bismuth oxychloride OREAL (FR) 2017-08-23 EP claimed
US-20170189278-A1 GEL-TYPE COSMETIC COMPOSITION L'OREAL (FR) 2017-07-06 US claimed
WO-2017063821-A1 COMPOSITION COMPRISING A SOFT-FOCUS FILLER AND A COMPOSITE PIGMENT BASED ON NON-SPHERICAL ALUMINA AND ON A METAL OXIDE L'OREAL (FR) 2017-04-20 WO claimed
US-11944698-B2 Dispersion with a dispersed fatty phase having a high pigment content CAPSUM (FR) 2024-04-02 US disclosed
US-11925699-B2 Gelled composition comprising a dispersion of solid aggregates L'OREAL (FR) 2024-03-12 US disclosed
WO-2023209015-A1 SOLID COSMETIC MAKE-UP COMPOSITION COMPRISING AT LEAST ONE CAVITY CAPSUM (FR) 2023-11-02 WO disclosed
CN-111511341-B Colored aqueous particle dispersion comprising at least one particulate dye, a matte effect filler, film-forming polymer particles, a thickener and an ionic polymer dispersant 莱雅公司 2023-10-03 CN disclosed
US-11744784-B2 Dyed particles with a high pigment content CAPSUM (FR) 2023-09-05 US disclosed
US-11111339-B2 Polyacrylate salt, methods of preparation and applications for employing the same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-09-07 US disclosed
US-20090016974-A1 Application of dehydroascorbic acid or derivatives/isomers thereof for artificially coloring the skin L'OREAL (FR) 2009-01-15 US disclosed
US-20090016971-A1 Aqueous fluid photoprotective compositions comprising tertiary-amide-terminated polyamide polymers L'OREAL (FR) 2009-01-15 US disclosed
US-20090018200-A1 COMPOSITION CONTAINING A PHENANTHRENOL L'OREAL (FR) 2009-01-15 US disclosed
US-20080226756-A1 COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND L'OREAL (FR) 2008-09-18 US disclosed
US-20080008673-A1 Compositions comprising at least one C-glycoside derivative L'OREAL S.A. (FR) 2008-01-10 US disclosed
US-20070248633-A1 COMPOSITIONS CONTAINING A HYDROXYLATED DIPHENYLMETHANE COMPOUND, METHODS OF USE L'OREAL (FR) 2007-10-25 US disclosed
US-20060134033-A1 Cosmetic composition with a lightening effect L'OREAL (FR) 2006-06-22 US disclosed