Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884381 | 0.87 | CYP11B1 (0.60) | CYP11B1CYP11B2HRH3TNFKDM4E | |
| SCHEMBL9337493 | 0.85 | MET (0.43) | CYP11B1CYP11B2HRH3BRD4SMN1; SMN2 | |
| SCHEMBL4142913 | 0.81 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFTDP1HTT | |
| SCHEMBL30826274 | 0.81 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFTDP1HTT | |
| Bromide SCHEMBL31253900 | 0.80 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFTDP1HTT | |
| Hydrochloric Acid SCHEMBL31253891 | 0.80 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFTDP1HTT | |
| SCHEMBL23781850 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2HRH3TNFKDM4E | |
| SCHEMBL8618130 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2TNFEGLN3HDAC1 | |
| SCHEMBL28996363 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2TNFHDAC1HDAC6 | |
| SCHEMBL9302460 | 0.77 | HDAC1 (0.71) | CYP11B1CYP11B2HRH3TNFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209046-A1 | Neutral Pharmaceuticals | MOULTON BRIAN DOUGLAS | 2009-08-20 | — | — | US | disclosed |
| WO-2007139731-A1 | NEUTRAL PHARMACEUTICALS | BROWN UNIVERSITY (US) | 2007-12-06 | — | — | WO | disclosed |