Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | FABP1 | P07148 | 1/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 2/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25262559 | 0.91 | RAB9A (0.79) | PTPN1KDM4ERAB9APTPN11MEN1 | |
| SCHEMBL677703 | 0.88 | RAB9A (0.86) | PTPN1KDM4ERAB9AMEN1LMNA | |
| SCHEMBL2835618 | 0.88 | PTPN1 (0.94) | PTPN1KDM4ERAB9AMEN1LMNA | |
| SCHEMBL22223650 | 0.88 | PTPN1 (0.94) | PTPN1KDM4ERAB9AMEN1LMNA | |
| SCHEMBL29611669 | 0.88 | PTPN1 (0.94) | PTPN1KDM4ERAB9AMEN1LMNA | |
| SCHEMBL19168006 | 0.84 | KDM4E (0.63) | PTPN1KDM4ERAB9APTPN11MEN1 | |
| SCHEMBL19168011 | 0.84 | KDM4E (0.63) | PTPN1KDM4ERAB9APTPN11MEN1 | |
| SCHEMBL5031589 | 0.84 | FABP1 (0.73) | PTPN1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22223646 | 0.84 | PTPN1 (0.76) | PTPN1KDM4ERAB9AMEN1LMNA | |
| SCHEMBL7232750 | 0.83 | KDM4E (0.74) | KDM4ERAB9APTPN11MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111236-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008087017-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | WO | disclosed |