SCHEMBL4359850

SCHEMBL4359850

COC(=O)c1ccc(OCCCCCc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
RAB9A P51151 3/20 0.70
PLA2G4B P0C869 1/20 0.65
FFAR1 O14842 2/20 0.61
S1PR1 P21453 3/20 0.59
S1PR3 Q99500 1/20 0.59
S1PR5 Q9H228 1/20 0.59
CYP4A11 Q02928 2/20 0.57
CYP4F2 P78329 1/20 0.57
NPC1 O15118 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NR1H4 Q96RI1 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
KDM4E B2RXH2 1/20 0.54
FAAH O00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4376261 1.00 MAPT (0.70) MAPTRAB9APLA2G4BFFAR1S1PR1
SCHEMBL4361268 0.99 MAPT (0.72) MAPTRAB9APLA2G4BFFAR1S1PR1
SCHEMBL4364300 0.94 MAPT (0.74) MAPTRAB9APLA2G4BFFAR1S1PR1
SCHEMBL4361298 0.90 MAPT (0.77) MAPTRAB9AFFAR1NPC1SMN1; SMN2
SCHEMBL14966681 0.88 MAPT (0.74) MAPTRAB9AFFAR1S1PR1S1PR3
SCHEMBL24844734 0.88 MAPT (0.90) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL2404460 0.88 CYP4A11 (0.73) MAPTRAB9ACYP4A11CYP4F2NPC1
SCHEMBL7776764 0.88 RAB9A (0.65) MAPTRAB9AFFAR1S1PR1S1PR3
SCHEMBL9241409 0.87 PLA2G4B (0.53) MAPTRAB9APLA2G4BFFAR1S1PR1
SCHEMBL5054312 0.86 MAPT (0.85) MAPTRAB9APLA2G4BNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1739071-B1 METHOD FOR PRODUCING CARBOXYLIC ACID COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-06-06 EP disclosed
CN-100554236-C The method for preparing carboxylic acid cpd SUMITOMO CHEMICAL CO (JP) 2009-10-28 CN disclosed
US-7511171-B2 Method for producing carboxylic acid compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-31 US disclosed
US-20070197824-A1 Method For Producing Carboxylic Acid Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-23 US disclosed
CN-1938253-A Process for producing carboxylic acid compound SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
EP-1739071-A1 METHOD FOR PRODUCING CARBOXYLIC ACID COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-01-03 EP disclosed
CN-1082023-A The medicine and the novel benzoic acid derivative that contain benzoic acid derivative YAMANOUCHI PHARMA CO LTD (JP) 1994-02-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197824-A1 Method For Producing Carboxylic Acid Compound COASY, CA9, CA7 MAPT 3874/4885RAB9A 1617/4885PLA2G4B 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.