Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.56 |
| ▸ | TLR2 | O60603 | 4/20 | 0.54 |
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4355580 | 0.97 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL2157081 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29352159 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL2089279 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL3624369 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29466503 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29514436 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29865029 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29602166 | 0.95 | TLR2 (0.58) | MDM2TLR2MDM4TP53KMT2A | |
| Hydrochloric Acid SCHEMBL25356870 | 0.94 | TLR2 (0.59) | MDM2TLR2MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923397-B1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-1923397-A1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-05-21 | — | — | EP | disclosed |