SCHEMBL4359997

SCHEMBL4359997

Cc1ccc2nc3ccccc3nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 5/20 1.00
ALDH1A1 P00352 4/20 0.67
KDM4E B2RXH2 3/20 0.67
L3MBTL1 Q9Y468 2/20 0.67
MAPT P10636 4/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
NPC1 O15118 2/20 0.54
POLB P06746 2/20 0.54
LMNA P02545 1/20 0.54
TDP1 Q9NUW8 3/20 0.53
USP2 O75604 1/20 0.52
CACNA1B Q00975 1/20 0.52
APBA1 Q02410 1/20 0.52
NR1I2 O75469 1/20 0.50
AHR P35869 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9927345 0.92 NQO2 (0.85) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL2756741 0.92 NQO2 (0.85) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL21131352 0.90 NQO2 (0.81) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL12355721 0.82 NQO2 (0.70) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL12355722 0.82 NQO2 (0.70) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL30745612 0.82 NQO2 (0.70) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL434975 0.82 NQO2 (0.70) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL17483584 0.82 NQO2 (0.68) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL17483582 0.82 NQO2 (0.68) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL13770454 0.82 NQO2 (0.68) NQO2ALDH1A1KDM4EL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2995601-B1 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND HAKUTO KK (JP) 2017-02-01 EP claimed
EP-2995601-A1 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND Hakuto Co., Ltd (JP) 2016-03-16 EP claimed
US-20090149682-A1 Process for Inhibiting Polymerization of an Aromatic Vinyl Compound HAKUTO CO., LTD. (JP) 2009-06-11 US claimed
EP-2000451-A9 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND Hakuto Co., Ltd (JP) 2009-03-25 EP claimed
EP-2000451-A2 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND Hakuto Co., Ltd (JP) 2008-12-10 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
CN-114717047-A Water-substitution-method stone-milled peanut oil production process 河南粒粒熟食品有限公司 2022-07-08 CN disclosed
WO-2021135182-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
WO-2019149260-A1 PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2019-08-08 WO disclosed
US-20180159141-A1 Non-Platinum Group Oxygen Reduction Reaction Catalysts BATTELLE SAVANNAH RIVER ALLIANCE, LLC 2018-06-07 US disclosed
EP-2170975-B1 COMPOSITIONS AND METHODS FOR PRODUCING CELLULAR LABELS FOR NUCLEAR MAGNETIC RESONANCE TECHNIQUES UNIV CARNEGIE MELLON (US) 2018-05-02 EP disclosed
EP-2995601-B1 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND HAKUTO KK (JP) 2017-02-01 EP disclosed
EP-2995601-A1 METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND Hakuto Co., Ltd (JP) 2016-03-16 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed
US-4792521-A Non-enzymatic immunohistochemical staining system and reagents IMMUNOMEDICS, INC. (US) 1988-12-20 US disclosed
EP-0250676-A2 Non-enzymatic immunohistochemical staining system and reagents Immunomedics, Inc. (US) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149682-A1 Process for Inhibiting Polymerization of an Aromatic Vinyl Compound VCP, PAH, VIM NQO2 2092/4885ALDH1A1 1616/4885KDM4E 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.