SCHEMBL436038

SCHEMBL436038

COCc1ccc([N+](=O)[O-])o1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MITF O75030 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TLR9 Q9NR96 1/20 0.39
GLO1 Q04760 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14613398 0.81 LMNA (0.56) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL1134756 0.81 LMNA (0.56) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL436082 0.81 LMNA (0.51) LMNAPOLBMEN1KMT2AALDH1A1
SCHEMBL18720617 0.81 LMNA (0.51) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL18742055 0.80 LMNA (0.50) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL11872132 0.79 LMNA (0.38) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL11872129 0.79 LMNA (0.38) LMNAPOLBKMT2ASMN1; SMN2ALDH1A1
SCHEMBL5543148 0.79 LMNA (0.53) LMNAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL28692684 0.79 LMNA (0.53) LMNAPOLBMEN1KMT2AALDH1A1
SCHEMBL14582812 0.79 LMNA (0.53) LMNAPOLBMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115029482-A CRISPR/cas12 a-mediated low-field nuclear magnetic resonance sensing detection system, and preparation method and application thereof 青岛市中心医院 2022-09-09 CN claimed
CN-111820225-B Herbicidal composition containing 3-aryl-6-trifluoromethylpyridazinol compound and application thereof 江苏清原农冠杂草防治有限公司 2022-04-05 CN claimed
CN-111820224-B Herbicidal composition containing trifluoromethyl pyridazinol compound and application thereof 江苏清原农冠杂草防治有限公司 2022-04-05 CN claimed
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
US-20190008993-A1 Compositions for Treating Biofilms and Methods for Using Same WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-01-10 US claimed
US-9884136-B2 Compositions for treating biofilms and methods for using same PLUROGEN THERAPEUTICS, INC. (US) 2018-02-06 US claimed
US-9872941-B2 Antimicrobial compositions and methods for locking catheters BECTON, DICKINSON AND COMPANY (US) 2018-01-23 US claimed
EP-3263145-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS Becton, Dickinson and Company (US) 2018-01-03 EP claimed
EP-1998825-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2017-10-18 EP claimed
US-20170216493-A1 Antimicrobial Compositions and Methods for Locking Catheters BECTON, DICKINSON AND COMPANY 2017-08-03 US claimed
US-6602496-B2 Applying polymerizable monomer and fungicide; applying to skins CLOSURE MEDICAL CORPORATION 2003-08-05 US claimed
US-6585967-B2 Adhesive treatment for tinea cruris CLOSURE MEDICAL CORPORATION 2003-07-01 US claimed
US-20030007826-A1 Adhesive treatment for tinea pedis CLOSURE MEDICAL CORPORATION 2003-01-09 US claimed
US-20030007947-A1 Adhesive treatment for oral fungal infection CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007946-A1 Adhesive treatment for tinea cruris CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007949-A1 Adhesive treatment for tinea corporis CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
US-20030007948-A1 Adhesive treatment for skin yeast infections CLOSURE MEDICAL CORPORATION (US) 2003-01-09 US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5635540-A STABLE MIXTURE OF ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER AND WATER AS CARRIER FOR ANTIBIOTICS, FUNGICIDES OR ANESTHETICS, FOR TREATING SKIN DISEASES, BURNS, WOUNDS THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 1997-06-03 US claimed