Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.82 |
| ▸ | CTSS | P25774 | 5/20 | 0.61 |
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941639 | 1.00 | CTSK (0.82) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL13909117 | 1.00 | CTSK (0.82) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4360850 | 1.00 | CTSK (0.82) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4360845 | 1.00 | CTSK (0.82) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL5942080 | 0.94 | CTSK (0.88) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL5942073 | 0.94 | CTSK (0.88) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4040287 | 0.93 | CTSK (0.82) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4369353 | 0.92 | CTSK (0.84) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4369360 | 0.92 | CTSK (0.84) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4369357 | 0.92 | CTSK (0.84) | CTSKCTSSCCR1CTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |