Diphenylmethane

Diphenylmethane

SCHEMBL4361124

c1ccc(Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 1.00
LTA4H P09960 1/20 0.57
IDH1 O75874 1/20 0.55
TSHR P16473 3/20 0.53
ALDH1A1 P00352 2/20 0.53
IDO1 P14902 1/20 0.53
TP53 P04637 1/20 0.53
LOXL2 Q9Y4K0 1/20 0.53
TRPA1 O75762 1/20 0.53
BCL2 P10415 1/20 0.52
BCL2L1 Q07817 1/20 0.52
PLA2G10 O15496 1/20 0.52
PLA2G2A P14555 1/20 0.52
LMNA P02545 1/20 0.52
SLC22A2 O15244 1/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
MAOB P27338 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL1303 1.00 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL3792579 1.00 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL28172316 1.00 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL14763944 1.00 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL25402252 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL2386917 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL544612 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL9958926 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL22462139 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL3750008 0.96 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7476465-B2 High density; stability; n-heterocyclic polymer or oligomer NEC CORPORATION (JP) 2009-01-13 US disclosed
US-7125614-B2 Organic electroluminescent device SAMSUNG SDI CO., LTD. (KR) 2006-10-24 US disclosed
US-20050100787-A1 High density; stability; n-heterocyclic polymer or oligomer NEC CORPORATION (JP) 2005-05-12 US disclosed
US-20040142209-A1 Organic electroluminescent device NEC CORPORATION (JP) 2004-07-22 US disclosed
US-6753097-B2 RED LIGHT EMISSION SAMSUNG SDI CO., LTD. (KR) 2004-06-22 US disclosed
US-20020028350-A1 Red light emission SAMSUNG DISPLAY CO., LTD. (KR) 2002-03-07 US disclosed
US-6329083-B1 RED LIGHT AT HIGHER BRIGHTNESS NEC CORPORATION (JP) 2001-12-11 US disclosed