Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358167 | 0.83 | ESR1 (0.47) | ESR1ESR2TLR8ALOX15HSD17B1 | |
| SCHEMBL3782742 | 0.76 | HDAC8 (0.50) | HDAC8HDAC6GAANPSR1MEN1 | |
| SCHEMBL2893593 | 0.72 | ESR1 (0.47) | ESR1ESR2TLR8ALOX15HSD17B1 | |
| SCHEMBL4358162 | 0.70 | ESR1 (0.45) | ESR1ESR2TLR8ALOX15HSD17B1 | |
| SCHEMBL8463060 | 0.69 | MCL1 (0.52) | ESR1ESR2ALOX15HSD17B1HSD17B2 | |
| SCHEMBL26856146 | 0.66 | ESR1 (0.42) | ESR1ESR2TLR8HSD17B1HSD17B2 | |
| SCHEMBL31435109 | 0.66 | HSD17B1 (0.42) | ESR1ESR2TLR8HSD17B1HSD17B2 | |
| SCHEMBL7232768 | 0.63 | CYP1A2 (0.48) | ESR1ESR2TLR8HSD17B1HSD17B2 | |
| SCHEMBL30118117 | 0.63 | CYP1A2 (0.48) | ESR1ESR2TLR8HSD17B1HSD17B2 | |
| SCHEMBL15451 | 0.63 | HSD17B1 (0.70) | ESR1ESR2TLR8HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619121-B2 | Method for isolating a thiol | UNIVERSITY OF CAPE TOWN (ZA) | 2009-11-17 | — | — | US | claimed |
| US-20070232836-A1 | Method for Isolating a Thiol | UNIVERSITY OF CAPE TOWN (ZA) | 2007-10-04 | — | — | US | claimed |
| WO-2005021493-A2 | A METHOD OF ISOLATING A THIOL | UNIVERSITY OF CAPE TOWN (ZA) | 2005-03-10 | — | — | WO | claimed |
| US-7619121-B2 | Method for isolating a thiol | UNIVERSITY OF CAPE TOWN (ZA) | 2009-11-17 | — | — | US | disclosed |
| US-20070232836-A1 | Method for Isolating a Thiol | UNIVERSITY OF CAPE TOWN (ZA) | 2007-10-04 | — | — | US | disclosed |
| WO-2005021493-A2 | A METHOD OF ISOLATING A THIOL | UNIVERSITY OF CAPE TOWN (ZA) | 2005-03-10 | — | — | WO | disclosed |