Methane

Methane

SCHEMBL436323

C.O=C(OO)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.64
▸ F2 P00734 1/20 0.64
▸ TSHR P16473 5/20 0.58
▸ MAPT P10636 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ TDP1 Q9NUW8 4/20 0.52
▸ HSD17B10 Q99714 3/20 0.52
▸ POLB P06746 2/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ PARP1 P09874 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ BLM P54132 1/20 0.52
▸ PMP22 Q01453 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ TP53 P04637 1/20 0.52
▸ ALDH1A1 P00352 4/20 0.50
▸ CES2 O00748 2/20 0.50
▸ CES1 P23141 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27894244 0.97 LMNA (0.61) LMNAF2TSHRMAPTKMT2A
Methane SCHEMBL27311569 0.97 LMNA (0.61) LMNAF2TSHRMAPTKMT2A
SCHEMBL27265493 0.97 LMNA (0.67) LMNAF2TSHRMAPTKMT2A
Hydrogen Peroxide SCHEMBL2929887 0.97 LMNA (0.67) LMNAF2TSHRMAPTKMT2A
Hydrogen Peroxide SCHEMBL11489043 0.97 LMNA (0.67) LMNAF2TSHRMAPTKMT2A
SCHEMBL1816 0.97 LMNA (0.67) LMNAF2TSHRMAPTKMT2A
Benzene SCHEMBL10686034 0.97 LMNA (0.67) LMNAF2TSHRMAPTKMT2A
Bicarbonate SCHEMBL9002401 0.95 LMNA (0.64) LMNAF2TSHRMAPTKMT2A
SCHEMBL11875365 0.95 LMNA (0.64) LMNAF2TSHRMAPTKMT2A
SCHEMBL10392799 0.95 LMNA (0.64) LMNAF2TSHRMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2108 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12016833-B2 Combination formulation containing colchicine for treatment or enhancing the therapy of liver disease ACEBIOMED, INC. (KR) 2024-06-25 — — US claimed
EP-3854390-A1 FORMULATION COMPRISING COLCHICINE AND METFORMINE FOR TREATMENT OR ENHANCING THE THERAPY OF LIVER DISEASE Acebiomed, Inc. (KR) 2021-07-28 — — EP claimed
US-20210220296-A1 COMBINATION FORMULATION CONTAINING COLCHICINE FOR TREATMENT OR ENHANCING THE THERAPY OF LIVER DISEASE ACEBIOMED, INC. 2021-07-22 — — US claimed
US-20210137858-A1 COMBINATION FORMULATION CONTAINING COLCHICINE FOR TREATMENT OR ENHANCING THE THERAPY OF LIVER DISEASE ACEBIOMED, INC. 2021-05-13 — — US claimed
US-20100081639-A1 PHARMACEUTICAL COMPOSITION COMPRISING FERMENTED GINSENG KIM DONG-HYUN 2010-04-01 — — US claimed
CN-101671596-A Detergent composition INFINEUM INT LTD 2010-03-17 — — CN claimed
US-6762145-B2 A OLEFIN POLYMERIZING CATALYST IS FORMED BY REACTING A HALOGENATED MAGNESIUM COMPOUND WITH ALCOHOL, REACTING THE SOLUTION WITH HYDROXY ESTER COMPOUND OR A PHOSPHORUS OR SILICON COMPOUND, REACTING THE INTERMEDIATE WITH TITANIUM SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2004-07-13 — — US claimed
US-20040068064-A1 Method for producing homo-and co-polymers of ethylene HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2004-04-08 — — US claimed
US-20040063875-A1 Method for producing homo-and co-polymers of ethylene SAMSUNG ATOFINA CO., LTD. (KR) 2004-04-01 — — US claimed
JP-2124533-A — — None — — JP disclosed
EP-4748400-A1 CONJUGATE FOR ANTIGEN DELIVERY AND USE THEREOF LG Chem, Ltd. (KR) 2026-05-27 — — EP disclosed
US-12637688-B2 DNA construct for diagnosing and treating cancer CNCURE BIOTECH INC. (KR) 2026-05-26 — — US disclosed
EP-4744674-A1 GASTRIC ACID-STABLE PROBIOTIC PREPARATION AND METHOD FOR PREPARING SAME Valvet Care Co., Ltd. (KR) 2026-05-20 — — EP disclosed
US-20260130988-A1 SARS-CoV-2 universal recombinant antigen polypeptides, polynucleotides and uses thereof KOREA NATIONAL INST OF HEALTH (KR) 2026-05-14 — — US disclosed
WO-1995022959-A2 SUNSCREEN COMPOSITIONS CIBA-GEIGY AG (CH) 1995-08-31 — — WO disclosed
EP-0432400-B1 Pharmacologically active substance BPC, the process for its preparation and its use in the therapy SIKIRIC PREDRAG (YU) 1995-07-19 — — EP disclosed
US-5378470-A Rectally administered pharmaceutical preparation HENNING BERLIN GMBH (DE) 1995-01-03 — — US disclosed
JP-H02124533-A LIQUID CRYSTAL ELECTROOPTICAL ELEMENT SEIKO EPSON CORP 1990-05-11 — — JP disclosed
EP-0352826-A2 Use of 5-aminosalicylic acid in the treatment of dermatological disorders TILLOTTS PHARMA AG (CH) 1990-01-31 — — EP disclosed
US-4526882-A Contacting magnesium alcoholate and group II or group IIIA metal alkyl, treating with titanium halide and electron donor, comminuting, treating product with titanium halide, ethyl benzoate, aromatic acid ester STANDARD OIL COMPANY (INDIANA) (US) 1985-07-02 — — US disclosed
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