SCHEMBL436335

SCHEMBL436335

CCOc1cc(S(=O)(=O)c2ccc(N)c(OCC)c2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
POLB P06746 4/20 0.59
MAPT P10636 4/20 0.59
MAPK1 P28482 2/20 0.59
HSD17B10 Q99714 2/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 1/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 2/20 0.47
PKM P14618 1/20 0.46
HTR6 P50406 1/20 0.46
HTT P42858 2/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26647136 0.88 ALDH1A1 (0.58) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL4651050 0.86 ALDH1A1 (0.56) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL23625105 0.85 ALDH1A1 (0.54) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL23625109 0.82 ALDH1A1 (0.47) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL5982727 0.79 HTT (0.41) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL3259829 0.79 TSHR (0.68) ALDH1A1POLBMAPTMAPK1HSD17B10
Sulfuric Acid SCHEMBL27584469 0.77 ALDH1A1 (0.58) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL2084753 0.77 HTT (0.67) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL11682228 0.76 CYP2D6 (0.56) ALDH1A1POLBMAPTMAPK1HSD17B10
SCHEMBL9442097 0.76 CA1 (0.50) ALDH1A1POLBMAPTMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
EP-1023168-B1 FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT US GOV SEC NAVY (US) 2004-11-24 EP claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
US-6001926-A Fiber-reinforced phthalonitrile composite cured with low-reactivity aromatic amine curing agent THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-12-14 US claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
US-20230023657-A1 Phthalonitrile Resins, Methods Of Making Same And Compositions Thereof HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2023-01-26 US disclosed
US-20220403108-A1 Curable Compositions Of Benzoxazine And Phthalonitrile Resins HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2022-12-22 US disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
WO-2021087197-A1 CURABLE COMPOSITIONS OF BENZOXAZINE AND PHTHALONITRILE RESINS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2021-05-06 WO disclosed
WO-2021087193-A1 PHTHALONITRILE RESINS, METHODS OF MAKING SAME AND COMPOSITIONS THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2021-05-06 WO disclosed
US-10765008-B2 Metal clad laminate, preparation method thereof, and method for preparing flexible circuit board by using the same ETERNAL MATERIALS CO., LTD. (TW) 2020-09-01 US disclosed
US-10731004-B2 Polyimide precursor composition and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-08-04 US disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026833-A CROSSLINKED FOAMS UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026904-A Aromatic epoxy-terminated polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3998786-A USEFUL FOR PREPARING COATINGS UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-21 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023657-A1 Phthalonitrile Resins, Methods Of Making Same And Compositions Thereof PNN, PAH, CUL4B ALDH1A1 2253/4885POLB 3255/4885MAPT 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.