SCHEMBL4363372

SCHEMBL4363372

O=C(Cc1ccccc1)OC(OC(=O)Cc1ccccc1)OC(OC(=O)Cc1ccccc1)OC(=O)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.67
MAPK1 P28482 2/20 0.55
ALDH1A1 P00352 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PAM P19021 1/20 0.53
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
AKR1B1 P15121 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
KLK7 P49862 2/20 0.43
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14332763 0.80 TSHR (0.67) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL29087553 0.80 TSHR (0.67) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL873430 0.80 TSHR (1.00) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL28112015 0.80 TSHR (0.67) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL8054787 0.78 TSHR (0.65) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL28134676 0.78 TSHR (0.76) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL27883126 0.78 TSHR (0.96) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL4911331 0.78 CRHBP (0.69) TSHRMAPK1ALDH1A1L3MBTL1PAM
SCHEMBL27120274 0.78 TSHR (0.76) TSHRMAPK1ALDH1A1L3MBTL1PAM
Hydrochloric Acid SCHEMBL27332250 0.78 TSHR (0.96) TSHRMAPK1ALDH1A1L3MBTL1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4438189-A POLYUNSATURATED COMPOUND, CROSSLINKABLE EPOXY OR METHYLOL COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-20 US claimed
US-20090292038-A1 Flame Retardant Photoimagable Coverlay Compositions and Methods Relating thereto E. I. DU PONT DE NEMOURS AND COMPANY 2009-11-26 US disclosed
US-7618766-B2 Flame retardant photoimagable coverlay compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-17 US disclosed
US-7527915-B2 Flame retardant multi-layer photoimagable coverlay compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US disclosed
US-20080033090-A1 Flame retardant multi-layer photoimagable coverlay compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-02-07 US disclosed
US-20070149635-A1 Flame retardant photoimagable coverlay compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-06-28 US disclosed
US-20050079442-A1 Halo resistent, photoimagable coverlay compositions, having advantageous application and removal properties, and methods relating thereto DUEBER THOMAS E (US) 2005-04-14 US disclosed
US-20040058276-A1 Halo resistent, photoimagable coverlay compositions, having, advantageous application and removal properties, and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-25 US disclosed
EP-1400545-A2 Halo resistant photoimagable coverlay compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-24 EP disclosed
US-6228919-B1 Solvent dispersible interpenetrating polymer networks E. I. DU PONT DE NEMOURS AND COMPANY 2001-05-08 US disclosed
US-5985998-A POLYMERS AND CROSSLINKING IN SOLVENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-16 US disclosed
US-5886101-A TWO INTERPENETRATING CROSSLINKED POLYMERS, AT LEAST ONE OF WHICH IS FORMED BY SOLVENT POLYMERIZATION; PHOTOSENSITIVE BINDERS OR SOLDER MASKS; PHOTORESISTS; PROTECTIVE AND DECORATIVE COATINGS; TOUGHNESS; FLEXIBILITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-23 US disclosed
EP-0501433-B1 Photosensitive compositions using solvent dispersible interpenetrating polymer networks DU PONT (US) 1997-05-07 EP disclosed
US-5536620-A ACRYLIC, POLYURETHANE ACRYLATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 US disclosed
EP-0501433-A1 Solvent dispersible interpenetrating polymer networks E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-02 EP disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed
US-4438189-A POLYUNSATURATED COMPOUND, CROSSLINKABLE EPOXY OR METHYLOL COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-20 US disclosed