SCHEMBL4363380

SCHEMBL4363380

NC(=O)c1cccnc1C1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UMPS P11172 1/20 0.51
HIF1A Q16665 1/20 0.43
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
EIF4E P06730 1/20 0.42
CYP3A4 P08684 1/20 0.42
TOP1 P11387 1/20 0.42
ADORA1 P30542 1/20 0.42
THPO P40225 1/20 0.42
PMP22 Q01453 1/20 0.42
MAPT P10636 2/20 0.42
CDA P32320 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6789387 1.00 UMPS (0.51) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
SCHEMBL6789391 1.00 UMPS (0.51) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
Phosphoric Acid SCHEMBL19057048 0.95 UMPS (0.47) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
Pyrophosphoric Acid SCHEMBL19057046 0.91 UMPS (0.44) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
SCHEMBL13725836 0.88 UMPS (0.40) UMPSLMNASMN1; SMN2ALDH1A1TSHR
SCHEMBL1034266 0.88 UMPS (0.40) UMPSLMNASMN1; SMN2ALDH1A1TSHR
SCHEMBL22092162 0.88 UMPS (0.43) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
SCHEMBL28708412 0.88 UMPS (0.43) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
SCHEMBL8973933 0.88 UMPS (0.43) UMPSHIF1ALMNASMN1; SMN2ALDH1A1
SCHEMBL30407484 0.85 SLC5A2 (0.43) UMPSHIF1ATSHRMAPTCDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586779-A Engineered cssDNA production hosts and phagemids 卡诺治疗公司 2026-02-27 CN claimed
WO-2017114796-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2017-07-06 WO claimed
EP-3187180-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE Ludwig-Maximilians-Universität München (DE) 2017-07-05 EP claimed
CN-121586779-A Engineered cssDNA production hosts and phagemids 卡诺治疗公司 2026-02-27 CN disclosed
WO-2024091038-A1 NOVEL BACTERIOPHAGES LBC1, LBC2, LEC1, LEC2, OR LSE1 AND USE THEREOF 한국식품연구원 2024-05-02 WO disclosed
CN-116004743-A Method and carrier for synthesizing nicotinamide mononucleotide by bacteria 常州大学 2023-04-25 CN disclosed
WO-2017114796-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2017-07-06 WO disclosed
EP-3187180-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE Ludwig-Maximilians-Universität München (DE) 2017-07-05 EP disclosed
US-20090186358-A1 Pathway Analysis of Cell Culture Phenotypes and Uses Thereof WYETH (US) 2009-07-23 US disclosed
WO-2007109363-A2 METHODS AND COMPOSITIONS FOR INHIBITING IMPDH ISOFORM 1 THE JOHNS HOPKINS UNIVERSITY (US) 2007-09-27 WO disclosed
EP-1765336-A2 ANGIOGENESIS INHIBITORS THE JOHNS-HOPKINS UNIVERSITY (US) 2007-03-28 EP disclosed
WO-2006004795-A2 ANGIOGENESIS INHIBITORS THE JOHNS HOPKINS UNIVERSITY (US) 2006-01-12 WO disclosed