Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401087 | 0.94 | MDM4 (0.60) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL29400989 | 0.94 | MDM4 (0.60) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL418101 | 0.94 | MDM4 (0.60) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL418102 | 0.94 | MDM4 (0.60) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL15806915 | 0.94 | MDM4 (0.60) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL23455559 | 0.93 | MDM4 (0.59) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL16620346 | 0.93 | MDM4 (0.59) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL31370422 | 0.93 | MDM4 (0.59) | MDM4TP53KMT2AMDM2CASP3 | |
| Trifluoroacetic Acid SCHEMBL4363443 | 0.91 | MDM2 (0.54) | MDM4TP53KMT2AMDM2CASP3 | |
| Trifluoroacetic Acid SCHEMBL4355580 | 0.89 | MDM2 (0.57) | MDM4TP53KMT2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923397-B1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-1923397-A1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-05-21 | — | — | EP | disclosed |