SCHEMBL436374

SCHEMBL436374

C[C@H](NC1(C)CCCC1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.44
RAB9A P51151 1/20 0.40
LTA4H P09960 1/20 0.37
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
FFAR3 O14843 1/20 0.32
TP53 P04637 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200644 1.00 MME (0.44) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL27524619 1.00 MME (0.44) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL203100 0.98 MME (0.43) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL6037209 0.98 MME (0.43) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL158231 0.98 MME (0.43) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL6102241 0.96 MME (0.41) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL6102246 0.96 MME (0.41) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL5328399 0.91 RAB9A (0.42) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL7848861 0.91 MME (0.39) MMERAB9ALTA4HTSHRNFKB1
SCHEMBL3418395 0.86 MME (0.36) MMERAB9ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 752 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064873-A2 COMPOSITIONS AND METHODS FOR TREATING CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2025-03-27 WO disclosed
EP-4400164-A2 A METHOD OF INDUCING CARDIOMYOCYTES PROLIFERATION AND TREATING HEART DISEASES Yeda Research and Development Co. Ltd (IL) 2024-07-17 EP disclosed
US-20240190919-A1 PEPTIDE COMPOUNDS AND THERAPEUTIC USES OF SAME IMMUNITY PHARMA LTD. (IL) 2024-06-13 US disclosed
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM ENTERA BIO LTD. (IL) 2024-06-06 US disclosed
US-20240182532-A1 MICROPEPTIDES AND USES THEREOF FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) 2024-06-06 US disclosed
US-20240094224-A1 ANTI-MICROBIAL PEPTIDE (AMP) SIGNATURES FOR DIAGNOSTICS, STRATIFICATION, AND TREATMENT OF MICROBIOME-ASSOCIATED DISEASE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-03-21 US disclosed
US-20240076346-A1 TYPE I MEMBRANE PROTEINS HETERODIMERS AND METHODS OF USE THEREOF KAHR MEDICAL LTD. (IL) 2024-03-07 US disclosed
US-11912790-B2 Peptide compounds and therapeutic uses of same IMMUNITY PHARMA LTD. (IL) 2024-02-27 US disclosed
US-20240042104-A1 METHOD OF INDUCING CARDIOMYOCYTES PROLIFERATION AND TREATING HEART DISEASES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-02-08 US disclosed
US-20240034753-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2024-02-01 US disclosed
WO-2001081540-A2 GROWTH FACTOR WHICH ACTS THROUGH ERB B-4 RTK YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2001-11-01 WO disclosed
EP-1080105-A1 PHENYLALANINE DERIVATIVES HAVING VLA-4 ANTAGONISTIC ACTIVITY CELLTECH THERAPEUTICS LIMITED (GB) 2001-03-07 EP disclosed
WO-2000001802-A2 PEPTIDE ANTAGONISTS OF THE HUMAN UROKINASE RECEPTOR AND METHOD FOR SELECTING THEM CANCERFORSKNINGSFONDEN AF 1989 (FONDEN TIL FREMME AF EKSPERIMENTEL CANCERFORSKNING) (DK) 2000-01-13 WO disclosed
WO-1999061465-A1 PHENYLALANINE DERIVATIVES HAVING VLA-4 ANTAGONISTIC ACTIVITY CELLTECH THERAPEUTICS LIMITED (GB) 1999-12-02 WO disclosed
EP-0842281-A1 PEPTIDE ANALOG INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1998-05-20 EP disclosed
EP-0672049-A4 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS. CHIRON MIMOTOPES PTY LTD (AU) 1997-10-15 EP disclosed
WO-1997005257-A1 PEPTIDE ANALOG INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1997-02-13 WO disclosed
EP-0672049-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1995-09-20 EP disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM PTH1R, PTMS, CYP24A1 MME 76/4885RAB9A 3480/4885LTA4H 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.