Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886376 | 0.84 | FLT3 (0.50) | FLT3NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4886383 | 0.84 | FLT3 (0.50) | FLT3NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4370967 | 0.84 | FLT3 (0.55) | FLT3ACP1MELK | |
| SCHEMBL4370973 | 0.84 | FLT3 (0.55) | FLT3ACP1MELK | |
| SCHEMBL4885754 | 0.80 | FLT3 (0.41) | FLT3NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4369838 | 0.80 | FLT3 (0.41) | FLT3NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4365972 | 0.72 | KMT2A (0.42) | NPC1LMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL14098400 | 0.71 | MEN1 (0.50) | FLT3NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14167507 | 0.69 | FLT3 (0.51) | FLT3ACP1MELK | |
| SCHEMBL14167789 | 0.68 | FLT3 (0.56) | FLT3ACP1MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046536-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS, INC. (CA) | 2009-04-16 | — | — | WO | disclosed |