Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8004873 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5176750 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5176686 | 0.76 | MCL1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL4950441 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2139854 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL61541 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL719237 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL376315 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL719494 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL965699 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325926-B1 | Metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2007-02-07 | — | — | EP | claimed |
| EP-3323823-B1 | METALLOCENE COMPOUND AND PREPARATION METHOD THEREFOR | HANWHA CHEMICAL CORP (KR) | 2020-01-29 | — | — | EP | disclosed |
| EP-1613797-B1 | MONOFILAMENTS OR STRETCHED TAPES FROM METALLOCENE-PRODUCED POLYETHYLENE | TOTAL RES & TECHNOLOGY FELUY (BE) | 2013-03-06 | — | — | EP | disclosed |
| US-7619106-B2 | Preparation of partially hydrogenated rac-ansa-metallocene complexes | BASELL POLYOLEFINE GMBH (DE) | 2009-11-17 | — | — | US | disclosed |
| US-20080200708-A1 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes | BASELL POLYOLEFINE GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1554295-B1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2008-07-02 | — | — | EP | disclosed |
| US-20070178303-A1 | Metallocene produced polyethylene for fibres applications | ATOFINA RESEARCH (BE) | 2007-08-02 | — | — | US | disclosed |
| EP-1364777-B1 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-6921563-B2 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-07-26 | — | — | US | disclosed |
| EP-1364777-A1 | Multi-layer laminate, packaging material and packages made therefrom | Ticona GmbH (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1153938-A1 | CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6153549-A | COORDINATION POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 2000-11-28 | — | — | US | disclosed |
| US-5883275-A | Process for the hydrogenation of metallocenes | TARGOR GMBH (DE) | 1999-03-16 | — | — | US | disclosed |