Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447974 | 0.90 | ABCB1 (0.36) | ABCB1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL435217 | 0.81 | OPRL1 (0.36) | ABCB1OPRL1 | |
| SCHEMBL434305 | 0.81 | ABCB1 (0.38) | ABCB1OPRL1 | |
| SCHEMBL28002997 | 0.73 | FEN1 (0.33) | — | |
| SCHEMBL29659605 | 0.71 | ABCB1 (0.44) | ABCB1OPRL1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL1865389 | 0.71 | KDM4E (0.48) | — | |
| SCHEMBL28209645 | 0.71 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL27898611 | 0.71 | PTGS1 (0.36) | ABCB1 | |
| SCHEMBL9137720 | 0.70 | — | — | |
| SCHEMBL27569086 | 0.70 | ABCB1 (0.61) | ABCB1OPRL1HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |