SCHEMBL435217

SCHEMBL435217

Fc1[c]ccc(Cl)c1C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 2/20 0.36
ABCB1 P08183 1/20 0.32
CEL P19835 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28209645 0.91 OPRL1 (0.33) OPRL1
SCHEMBL433498 0.83 CEL (0.33) OPRL1CEL
SCHEMBL436492 0.81 ABCB1 (0.40) OPRL1ABCB1
SCHEMBL434305 0.75 ABCB1 (0.38) OPRL1ABCB1CEL
SCHEMBL457959 0.72 PTGS1 (0.31) OPRL1
SCHEMBL6447974 0.71 ABCB1 (0.36) ABCB1
SCHEMBL4689694 0.70 OPRL1 (0.61) OPRL1ABCB1
SCHEMBL28002997 0.70 FEN1 (0.33) CEL
SCHEMBL10693537 0.70 SMN1; SMN2 (0.47) OPRL1ABCB1CEL
SCHEMBL3958803 0.68 CYP2D6 (0.32) CEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2595984-A1 MICROBICIDES Syngenta Participations AG (CH) 2013-05-29 EP disclosed
EP-2595985-A1 ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES Syngenta Participations AG (CH) 2013-05-29 EP disclosed
WO-2012010568-A1 MICROBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-26 WO disclosed
WO-2012010567-A1 ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-26 WO disclosed