⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493268 | 0.78 | — | — | |
| SCHEMBL8023862 | 0.73 | — | — | |
| SCHEMBL7510901 | 0.73 | — | — | |
| SCHEMBL4057454 | 0.73 | — | — | |
| SCHEMBL14667647 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL10647559 | 0.72 | — | — | |
| SCHEMBL16969672 | 0.72 | — | — | |
| SCHEMBL3363269 | 0.72 | — | — | |
| SCHEMBL10530779 | 0.69 | — | — | |
| SCHEMBL8831187 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149324-B | Synthesis method of 6-hydroxy-8-chlorooctanoic acid ethyl ester, 6, 8-dichloro octanoic acid ethyl ester and lipoic acid | 厦门金达威维生素有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114149324-A | Synthesis method of 6-hydroxy-8-chloro ethyl caprylate, 6, 8-dichloro ethyl caprylate and lipoic acid | 厦门金达威维生素有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-112741815-A | Novel antidepressant sustained and controlled release drug delivery system | 江苏集萃新型药物制剂技术研究所有限公司 | 2021-05-04 | — | — | CN | disclosed |
| EP-1731499-B1 | PROCESS FOR PRODUCING 1,2-CIS-2-FLUOROCYCLOPROPANE-1-CARBOXYLIC ESTER COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20090162290-A1 | METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF | THERAPHARM GMBH | 2009-06-25 | — | — | US | disclosed |
| US-20080312430-A1 | Method of Preparing or Synthesizing Polyazamacrocycle Derivatives | THERAPHARM GMBH (CH) | 2008-12-18 | — | — | US | disclosed |
| US-7381833-B2 | Process for producing 1,2-cis-2-fluorocyclopropane-1-carboxylic ester compound | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-06-03 | — | — | US | disclosed |
| US-20070191626-A1 | Process for producing 1,2-cis-2 fluorocyclopropane- 1carboxylic ester compound | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1731499-A1 | PROCESS FOR PRODUCING 1,2-CIS-2-FLUOROCYCLOPROPANE-1CARBOXYLIC ESTER COMPOUND | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-0671386-B1 | Monomers derived from perhalogeneted sultones and polymers derived therefrom | CENTRE NAT RECH SCIENT (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0410881-B1 | Semisynthetic ganglioside analogues | FIDIA SPA (IT) | 1997-09-17 | — | — | EP | disclosed |
| US-5484775-A | FOR INHIBITING GLUTAMATE-INDUCED NEUROTOXICITY | FIDIA S.P.A. (IT) | 1996-01-16 | — | — | US | disclosed |
| EP-0671386-A1 | Monomers derived from perhalogeneted sultones and polymers derived therefrom | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-4243661-A | MULTHIOMYCIN ANTIBIOTIC | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-01-06 | — | — | US | disclosed |
| US-4229535-A | CULTIVATING STREPTOMYCES STRAIN IN MEDIUM CONTAINING CYSTINE OR METHIONINE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1980-10-21 | — | — | US | disclosed |