Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366273 | 1.00 | DDB1 (0.44) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL4373314 | 1.00 | DDB1 (0.44) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL4363986 | 0.93 | CRBN (0.48) | DDB1CRBNOPRM1TNFIL1B | |
| SCHEMBL4362085 | 0.93 | CRBN (0.48) | DDB1CRBNOPRM1TNFIL1B | |
| SCHEMBL4363944 | 0.93 | CRBN (0.48) | DDB1CRBNOPRM1TNFIL1B | |
| SCHEMBL13952251 | 0.88 | DDB1 (0.42) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL14602355 | 0.83 | OPRM1 (0.49) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL1265932 | 0.81 | OPRM1 (0.50) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL30998388 | 0.81 | OPRM1 (0.50) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL1264462 | 0.81 | OPRM1 (0.50) | DDB1CRBNOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026248-A2 | HYDRAZIDE, AMIDE, PHTHALIMIDE AND PHTHALHYDRAZIDE ANALOGS AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-02-26 | — | — | WO | claimed |
| WO-2009026248-A2 | HYDRAZIDE, AMIDE, PHTHALIMIDE AND PHTHALHYDRAZIDE ANALOGS AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-02-26 | — | — | WO | disclosed |