Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198659 | 0.83 | ALB (0.51) | HAVCR2ALBAURKARAB9AKMT2A | |
| SCHEMBL2719152 | 0.81 | HAVCR2 (0.52) | HAVCR2ALBAURKARAB9AKMT2A | |
| SCHEMBL436943 | 0.81 | HAVCR2 (0.56) | HAVCR2RAB9AKMT2ANPC1KDM4E | |
| SCHEMBL436434 | 0.81 | HAVCR2 (0.68) | HAVCR2RAB9AKMT2ANPC1KDM4E | |
| SCHEMBL10126289 | 0.81 | HAVCR2 (0.68) | HAVCR2AURKAPARP1BTKG6PD | |
| SCHEMBL436716 | 0.81 | HAVCR2 (1.00) | HAVCR2AURKARAB9AKMT2ANPC1 | |
| SCHEMBL437026 | 0.81 | HAVCR2 (0.68) | HAVCR2AURKARAB9AKMT2ANPC1 | |
| SCHEMBL440043 | 0.79 | KMT2A (0.68) | RAB9AKMT2ANPC1KDM4EMAPK1 | |
| SCHEMBL26167923 | 0.79 | HAVCR2 (0.54) | HAVCR2AURKARAB9AKMT2ANPC1 | |
| SCHEMBL442207 | 0.79 | HAVCR2 (0.65) | HAVCR2RAB9AKMT2ANPC1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |