Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 1.00 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494135 | 0.84 | HAVCR2 (0.72) | HAVCR2NR4A2TSHRALDH1A1KMT2A | |
| SCHEMBL11867822 | 0.83 | HAVCR2 (0.70) | HAVCR2NR4A2TSHRALDH1A1KMT2A | |
| SCHEMBL439785 | 0.81 | HAVCR2 (0.68) | HAVCR2TSHRALDH1A1KMT2ARAB9A | |
| SCHEMBL437026 | 0.81 | HAVCR2 (0.68) | HAVCR2NR4A2KMT2ARAB9ANPC1 | |
| SCHEMBL436434 | 0.81 | HAVCR2 (0.68) | HAVCR2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL436633 | 0.81 | HAVCR2 (0.68) | HAVCR2KMT2ARAB9ANPC1BTK | |
| Hydrochloric Acid SCHEMBL11869520 | 0.81 | HAVCR2 (0.68) | HAVCR2NR4A2TSHRALDH1A1KMT2A | |
| SCHEMBL10126289 | 0.81 | HAVCR2 (0.68) | HAVCR2BTKAURKAPARP1G6PD | |
| SCHEMBL437260 | 0.80 | HAVCR2 (0.67) | HAVCR2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL440425 | 0.79 | KMT2A (0.68) | HAVCR2ALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |