Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828113 | 0.93 | KDM4E (0.56) | NR4A2CHEK2HSP90AA1ESR2TDP1 | |
| SCHEMBL20982594 | 0.92 | NR4A2 (0.77) | NR4A2CHEK2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL28930292 | 0.85 | KDM4E (0.68) | NR4A2CHEK2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL20982644 | 0.85 | NR4A2 (0.86) | NR4A2CHEK2HSP90AA1ESR2TDP1 | |
| SCHEMBL7602620 | 0.84 | KDM4E (0.70) | NR4A2CHEK2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL5219768 | 0.84 | NR4A2 (0.83) | NR4A2CHEK2MMP2MMP9MMP8 | |
| SCHEMBL3178116 | 0.83 | CHEK2 (0.78) | NR4A2CHEK2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL28722299 | 0.83 | NR4A2 (0.72) | NR4A2CHEK2HSP90AA1ESR2TDP1 | |
| SCHEMBL8611783 | 0.83 | KDM4E (0.69) | NR4A2CHEK2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL28722301 | 0.83 | KDM4E (0.61) | NR4A2CHEK2HSP90AA1ESR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081913-A2 | BENZIMIDAZOLE,BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES, OPTICAL FILM COMPRISING THEM AND METHOD OF PRODUCTION THEREOF | CRYSOPTIX K.K. (JP) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008020211-A2 | BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES, OPTICAL FILM COMPRISING THEM AND METHOD OF PRODUCTION THEREOF | CRYSOPTIX K.K. (JP) | 2008-02-21 | — | — | WO | disclosed |