Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 8/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366407 | 0.93 | NR4A2 (0.65) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28930292 | 0.91 | KDM4E (0.68) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7602620 | 0.90 | KDM4E (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28722301 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8611783 | 0.89 | KDM4E (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL31533522 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL12471017 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL20982594 | 0.86 | NR4A2 (0.77) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6220033 | 0.86 | PKN1 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL31412081 | 0.86 | KDM4E (0.79) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291703-B1 | COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL | CRYSOPTIX KK (JP) | 2016-11-30 | — | — | EP | disclosed |
| EP-2135889-B1 | FLUORINATED POLYETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND CURABLE COMPOSITION CONTAINING THE SAME | UNIMATEC CO LTD (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-8142863-B2 | Color liquid crystal display and compensation panel | Crysoptix, KK (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20100279122-A1 | Benzimidazole, Benzoxazole and Benzothiazole Derivatives, Optical Film Comprising them and Method of Producing thereof | CRYSOPTIX KK (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2135889-A1 | FLUORINATED POLYETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND CURABLE COMPOSITION CONTAINING THE SAME | Unimatec Co., Ltd. (JP) | 2009-12-23 | — | — | EP | disclosed |
| US-20090268136-A1 | Color Liquid Crystal Display and Compensation Panel | CRYSOPTIX KK (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-2081913-A2 | BENZIMIDAZOLE,BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES, OPTICAL FILM COMPRISING THEM AND METHOD OF PRODUCTION THEREOF | CRYSOPTIX K.K. (JP) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008020211-A2 | BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES, OPTICAL FILM COMPRISING THEM AND METHOD OF PRODUCTION THEREOF | CRYSOPTIX K.K. (JP) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279122-A1 | Benzimidazole, Benzoxazole and Benzothiazole Derivatives, Optical Film Comprising them and Method of Producing thereof | BMX, ABCG2, BRI3BP | KDM4E 1712/4885ALDH1A1 1696/4885HPGD 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.