Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.80 |
| ▸ | CTSS | P25774 | 5/20 | 0.59 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941951 | 1.00 | CTSK (0.80) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4366569 | 1.00 | CTSK (0.80) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4040302 | 1.00 | CTSK (0.80) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL5941884 | 0.94 | CTSK (0.76) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4361906 | 0.94 | CTSK (0.76) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4043101 | 0.94 | CTSK (0.76) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4361912 | 0.94 | CTSK (0.76) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4041612 | 0.94 | CTSK (0.76) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4368912 | 0.93 | CTSK (0.75) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4044020 | 0.93 | CTSK (0.75) | CTSKCTSSCTSVCTSLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |