Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749806 | 0.98 | MEN1 (0.50) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL7755866 | 0.95 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL18357952 | 0.95 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL11045236 | 0.93 | TSHR (0.50) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL15965444 | 0.91 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL12970038 | 0.91 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL11387775 | 0.88 | TSHR (0.46) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL7953289 | 0.87 | MEN1 (0.42) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL28810887 | 0.86 | MEN1 (0.48) | MEN1KMT2APOLBTSHRMAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9241877 | 0.85 | MAPK1 (0.59) | MEN1KMT2APOLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088489-A1 | AMINE CATALYSTS SUITABLE FOR PRODUCING LOW-EMANATION, RECATALYSIS-STABLE FLEXIBLE POLYURETHANE FOAMS | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-04-02 | — | — | US | disclosed |