Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749806 | 0.89 | MEN1 (0.50) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL5933721 | 0.89 | MEN1 (0.50) | MEN1KMT2APOLBTSHRALDH1A1 | |
| SCHEMBL25529334 | 0.87 | MEN1 (0.48) | MEN1KMT2APOLBTSHRALDH1A1 | |
| SCHEMBL7755866 | 0.87 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| Ammonia Solution, Strong SCHEMBL4366934 | 0.87 | MEN1 (0.48) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL18357952 | 0.87 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL11045236 | 0.85 | TSHR (0.50) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL12970038 | 0.83 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL15965444 | 0.83 | MEN1 (0.52) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL11387775 | 0.81 | TSHR (0.46) | MEN1KMT2APOLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102787-A1 | 2'-O-AMINOETHYLOXYETHYL-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008044-A1 | 2'-O-AMINOETHYLOXYETHYL-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-17 | — | — | WO | disclosed |