SCHEMBL436702

SCHEMBL436702

CC1c2ccccc2Oc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
ATM Q13315 1/20 0.48
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
USP2 O75604 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29797921 1.00 MAOA (0.58) MAOAMAOBATMMEN1KMT2A
SCHEMBL10692504 0.86 MAOA (0.45) MAOAMAOBATMMEN1KMT2A
SCHEMBL12205445 0.84 KMT2A (0.46) MAOAMAOBATMMEN1KMT2A
SCHEMBL10967593 0.83 MAOA (0.46) MAOAMAOBATMMEN1KMT2A
SCHEMBL31545095 0.82 MEN1 (0.48) MAOAMAOBATMMEN1KMT2A
SCHEMBL12891380 0.81 MAOA (0.45) MAOAMAOBATMMEN1KMT2A
SCHEMBL29767372 0.81 MAOA (0.45) MAOAMAOBATMMEN1KMT2A
SCHEMBL2407012 0.81 MAOA (0.45) MAOAMAOBATMMEN1KMT2A
SCHEMBL29473842 0.81 MAOA (0.45) MAOAMAOBATMMEN1KMT2A
SCHEMBL15147092 0.81 MAOA (0.45) MAOAMAOBATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551069-B Near-infrared methyl xanthene dye and preparation method and application thereof 临沂大学 2025-03-04 CN claimed
CN-117551069-A Near-infrared methyl xanthene dye and preparation method and application thereof 临沂大学 2024-02-13 CN claimed
CN-109879713-A A kind of preparation method of trans- four substituted olefines derivative 华侨大学 2019-06-14 CN claimed
US-8030096-B2 Water-soluble rhodamine dyes conjugates APPLIED BIOSYSTEMS LLC (US) 2011-10-04 US claimed
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates Life Technologies Corporation (US) 2011-04-07 US claimed
US-7795042-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC (US) 2010-09-14 US claimed
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates APPLIED BIOSYSTEMS INC. (US) 2009-12-10 US claimed
US-7504496-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC 2009-03-17 US claimed
US-20070077222-A1 Composition and treatment for hair loss RETAINE PRODUCTS, LLC. 2007-04-05 US claimed
JP-3719979-B2 2005-11-24 JP claimed
EP-0771196-A4 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1997-09-03 EP claimed
WO-1997025351-A2 INHIBITORS OF MAdCAM-1-MEDIATED INTERACTIONS AND METHODS OF USE THEREFOR LEUKOSITE, INC. (US) 1997-07-17 WO claimed
EP-0771196-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-05-07 EP claimed
US-5614550-A ANTICHOLESTEROL AGENTS OR ARTERIOSCLEROSIS AGENTS FOR HUMANS SANKYO COMPANY, LIMITED (JP) 1997-03-25 US claimed
US-5534529-A Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 1996-07-09 US claimed
WO-1996007405-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-03-14 WO claimed
EP-0632036-A2 Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1995-01-04 EP claimed
US-5227560-A Vinylene or exomethylene groups from active methine compounds THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
US-5101059-A Xanthene compounds RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-03-31 US claimed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates SLC43A3, ABCG2, TARBP1 MAOA 4751/4885MAOB 4447/4885ATM 4074/4885
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates SLC43A3, ABCG2, TARBP1 MAOA 4751/4885MAOB 4416/4885ATM 3999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.