Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838858 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53LMNAF2 | |
| Water SCHEMBL27446036 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53LMNAF2 | |
| Water SCHEMBL27446035 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL6658799 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL6659868 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL670258 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL1162598 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL582331 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRTP53LMNAF2 | |
| SCHEMBL420405 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRTP53LMNAF2 | |
| Water SCHEMBL1660792 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRTP53LMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959870-B | Preparation of morpholine derivatives | SANDOZ AG | 2013-10-16 | — | — | CN | claimed |
| CN-101959870-A | Preparation of morpholine derivatives | SANDOZ AG | 2011-01-26 | — | — | CN | claimed |
| CN-101514163-A | Optically pure Sibutramine and process for preparing salt derivative thereof | GUANGZHOU HUIHONG BIOPHARMACEU (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-101137654-A | Novel salt of quinuclidine derivative | ASTELLAS PHARMA INC (JP) | 2008-03-05 | — | — | CN | claimed |
| CN-1315777-C | Process for recovering optically active diacyltartaric acids | TORAY FINECHEMICALS CO LTD (JP) | 2007-05-16 | — | — | CN | claimed |
| CN-1738791-A | Process for recovering optically active diacyltartaric acids | TORAY FINECHEMICALS CO LTD (JP) | 2006-02-22 | — | — | CN | claimed |
| CN-1729192-A | Optical resolution of (1-benzyl-4-methylpiperidin-3-yl) -methylamine and the use thereof for the preparation of pyrrolo 2,3-pyrimidine derivatives as protein kinases inhibitors | PFIZER PROD INC (US) | 2006-02-01 | — | — | CN | claimed |
| CN-1211366-C | Methyl sulfonate trihydrate of 1-(4-hydroxy phenyl)-2-(4-hydroxy-4-phenyl piperid-1-yl)-1-propanol and its intermidiate preparing process | PFIZER PROD INC (US) | 2005-07-20 | — | — | CN | claimed |
| CN-1322716-A | Methyl sulfonate trihydrate of 1-(4-hydroxy phenyl)-2-(4-hydroxy-4-phenyl piperid-1-yl)-1-propanol and its intermidiate preparing process | PFIZER PROD INC (US) | 2001-11-21 | — | — | CN | claimed |
| US-6194593-B1 | USEFUL AS LIGAND FOR AN ASYMMETRIC CATALYST FOR USE IN ASYMMETRICAL HYDROGENATION | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2001-02-27 | — | — | US | claimed |
| CN-87102402-A | New optically-active compound | — | 1987-10-07 | — | — | CN | claimed |
| CN-114524812-A | Crystal form preparation and synthesis method of 1, 4-dihydro-1, 6-naphthyridine compound | 湖南凯铂生物药业有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110724146-B | Preparation method of tofacitinib citrate | 四川大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-113214270-A | Compounds and derivatives thereof as MDM2-P53 inhibitors | 勃林格殷格翰国际有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-108137590-B | Spiro (3H-indol-3, 2' -pyrrolidin) -2(1H) -one compounds and their derivatives as MDM2-P53 inhibitors | 勃林格殷格翰国际有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-87102402-A | New optically-active compound | — | 1987-10-07 | — | — | CN | disclosed |
| EP-0140830-A2 | Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture | Zyma SA (CH) | 1985-05-08 | — | — | EP | disclosed |
| EP-0139615-A2 | Flavene and thioflavene derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |
| EP-0074903-A2 | Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene, their preparation and their therapeutic use | SYNTHELABO (FR) | 1983-03-23 | — | — | EP | disclosed |
| US-4110360-A | FROM AN ALDEHYDE, ACID HALIDE AND CYANIDE | SHELL OIL COMPANY (US) | 1978-08-29 | — | — | US | disclosed |