⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373236 | 0.90 | — | — | |
| SCHEMBL4374384 | 0.90 | S1PR2 (0.32) | — | |
| SCHEMBL2017258 | 0.86 | — | — | |
| SCHEMBL1763282 | 0.86 | — | — | |
| SCHEMBL13535333 | 0.86 | — | — | |
| SCHEMBL4369973 | 0.80 | S1PR2 (0.38) | — | |
| SCHEMBL13127200 | 0.75 | — | — | |
| SCHEMBL24577684 | 0.75 | S1PR2 (0.42) | — | |
| SCHEMBL8290708 | 0.75 | CYP2C9 (0.38) | — | |
| SCHEMBL1722167 | 0.75 | CYP2C9 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738647-B2 | Methods for the synthesis of polycyclic guanidine compounds | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-08-22 | — | — | US | disclosed |
| US-20140194622-A1 | METHODS FOR THE SYNTHESIS OF POLYCYCLIC GUANIDINE COMPOUNDS | NOVOMER, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8642771-B2 | Methods for the synthesis of polycyclic guanidine compounds | NOVOMER, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-20120259112-A1 | METHODS FOR THE SYNTHESIS OF POLYCYCLIC GUANIDINE COMPOUNDS | NOVOMER, INC. (US) | 2012-10-11 | — | — | US | disclosed |
| US-8212037-B2 | Process for production of optically active quinuclidinols | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20090216019-A1 | Process for Production of Optically Active Quinuclidinols | KANTO KAGAKU KABUSHIKI KAISHA | 2009-08-27 | — | — | US | disclosed |
| EP-1867654-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE QUINUCLIDINOL | Nagoya Industrial Science Research Institute (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-1096931-A2 | USE OF (S) (-)-AMISULPRIDE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF SCHIZOPHRENIA | SANOFI-SYNTHELABO (FR) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003740-A2 | USE OF (S) (-)-AMISULPRIDE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF SCHIZOPHRENIA | SANOFI-SYNTHELABO (FR) | 2000-01-27 | — | — | WO | disclosed |