SCHEMBL4368482

SCHEMBL4368482

O=C1c2cccc3cccc(c23)C2SC12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
CES2 O00748 1/20 0.42
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
MCL1 Q07820 1/20 0.42
TYMS P04818 5/20 0.40
PARP1 P09874 1/20 0.38
PABPC1 P11940 3/20 0.37
DNMT1 P26358 2/20 0.37
CYP3A4 P08684 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ERCC1 P07992 1/20 0.36
FEN1 P39748 1/20 0.36
ERCC4 Q92889 1/20 0.36
HSD17B10 Q99714 4/20 0.35
MAPK1 P28482 2/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123021 0.73 ALDH1A1 (0.45) ALDH1A1CES2BCHECES1MCL1
SCHEMBL8363928 0.73 ALDH1A1 (0.45) ALDH1A1CES2BCHECES1MCL1
SCHEMBL6880786 0.73 ALDH1A1 (0.45) ALDH1A1CES2BCHECES1MCL1
SCHEMBL26773869 0.72 MEN1 (0.54) ALDH1A1CES2BCHECES1MCL1
SCHEMBL24782332 0.69 ALDH1A1 (0.41) ALDH1A1CES2BCHECES1MCL1
SCHEMBL12486737 0.69 HEXA (0.41) ALDH1A1CES2BCHECES1MCL1
SCHEMBL10611039 0.69 HSD17B10 (0.43) ALDH1A1CES2BCHECES1MCL1
SCHEMBL22000513 0.69 CYP1B1 (0.43) ALDH1A1CES2BCHECES1MCL1
SCHEMBL18380938 0.69 ALDH1A1 (0.41) ALDH1A1CES2BCHECES1MCL1
SCHEMBL23300517 0.68 ALDH1A1 (0.40) ALDH1A1CES2BCHECES1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107250267-B Corrosion resistant flame retardant formulations for thermoplastic polymers 科莱恩国际有限公司 2022-10-04 CN disclosed
US-11053375-B2 Anticorrosive flame retardant formulations for thermoplastic polymers CLARIANT PLASTICS & COATINGS LTD (CH) 2021-07-06 US disclosed
US-20180171112-A1 ANTICORROSIVE FLAME RETARDANT FORMULATIONS FOR THERMOPLASTIC POLYMERS CLARIANT PLASTICS & COATINGS LTD (CH) 2018-06-21 US disclosed
CN-103168071-B Flame-retardant polyester compounds CLARIANT FINANCE BVI LTD 2015-03-25 CN disclosed
CN-103384658-A Impact modified poly(butylene terephthalate) ester compositions, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP 2013-11-06 CN disclosed
US-20130210968-A1 Flame-Retardant Polyester Compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2013-08-15 US disclosed
CN-103168071-A Flame-retardant polyester compounds CLARIANT INT LTD 2013-06-19 CN disclosed
CN-100567371-C Polyarylene sulfide oxide, solid article and manufacture method thereof TORAY IND LTD (JP) 2009-12-09 CN disclosed
JP-2009179918-A BRAID AND ELECTRICALLY INSULATED SLEEVE TORAY IND INC 2009-08-13 JP disclosed
JP-2009084713-A POLYPHENYLENE SULFIDE PAPER, POLYPHENYLENE SULFIDE OXIDE PAPER, AND METHOD FOR PRODUCING THEM TORAY IND INC 2009-04-23 JP disclosed
US-20090088512-A1 Flame-retardant compounded polyester materials CLARIANT INTERNATIONAL LTD. 2009-04-02 US disclosed
CN-1989177-A Polyarylene sulfide oxide, solid article and process for producing the same TORAY IND LTD (JP) 2007-06-27 CN disclosed