Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.66 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.66 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362694 | 0.92 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4375118 | 0.92 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4364755 | 0.92 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4361568 | 0.90 | KIF11 (0.70) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4371805 | 0.90 | KIF11 (0.66) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4363688 | 0.89 | KIF11 (0.73) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4368870 | 0.89 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL5392779 | 0.88 | KIF11 (0.74) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL5396009 | 0.88 | KIF11 (0.73) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL13956818 | 0.87 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482343-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2009-01-27 | — | — | US | disclosed |