Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.36 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | RAD52 | P43351 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560722 | 0.98 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL5287061 | 0.98 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL4222967 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL4365554 | 0.98 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL19461099 | 0.98 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| Bromide SCHEMBL15798172 | 0.97 | HTT (0.39) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| Bromide SCHEMBL15798392 | 0.97 | HTT (0.39) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL4364560 | 0.96 | KMT2A (0.37) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL18342039 | 0.95 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL4071944 | 0.95 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102419-A2 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2009-08-20 | — | — | WO | claimed |
| EP-2931852-A1 | IONIC LIQUIDS AS LUBRICATING OIL BASE STOCKS, COBASE STOCKS AND MULTIFUNCTIONAL FUNCTIONAL FLUIDS | ExxonMobil Research and Engineering Company (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014092939-A1 | IONIC LIQUIDS AS LUBRICATING OIL BASE STOCKS, COBASE STOCKS AND MULTIFUNCTIONAL FUNCTIONAL FLUIDS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2009102419-A2 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2009-08-20 | — | — | WO | disclosed |