Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243911 | 0.95 | ESR1 (0.50) | PTPN11S1PR3TP53TSHRPPARG | |
| SCHEMBL9323929 | 0.88 | NR5A1 (0.63) | PTPN11NR5A1TP53TSHRPLA2G4B | |
| SCHEMBL9067305 | 0.86 | PTPN11 (0.68) | PTPN11TP53TSHRPLA2G4B | |
| SCHEMBL7820620 | 0.86 | PTPN11 (0.64) | PTPN11S1PR3TP53TSHRPLA2G4B | |
| SCHEMBL5492191 | 0.86 | PTPN11 (0.64) | PTPN11S1PR3TP53TSHRPLA2G4B | |
| SCHEMBL27494596 | 0.86 | PTPN11 (0.68) | PTPN11TP53TSHRPLA2G4B | |
| SCHEMBL23067536 | 0.85 | PTPN11 (0.51) | PTPN11NR5A1TP53TSHRCYSLTR2 | |
| SCHEMBL12121011 | 0.84 | PTPN11 (0.58) | PTPN11S1PR3TP53PTPN1PTPN6 | |
| SCHEMBL29654165 | 0.84 | PTPN11 (0.58) | PTPN11S1PR3TP53PTPN1PTPN6 | |
| SCHEMBL28193088 | 0.84 | PTPN11 (0.66) | PTPN11TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744792-B1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES GMBH (CH) | 2018-11-28 | — | — | EP | claimed |
| US-8211351-B2 | Resorbable polymeric medical goods with improved mechanical properties and method for producing same | SYNTHES USA, LLC (US) | 2012-07-03 | — | — | US | claimed |
| US-20090030415-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES USA, LLC | 2009-01-29 | — | — | US | claimed |
| EP-1744792-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | Synthes GmbH (CH) | 2007-01-24 | — | — | EP | claimed |
| WO-2005110506-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES GMBH (CH) | 2005-11-24 | — | — | WO | claimed |